In Europe, there are barriers to the inclusion of 12- to 25-year-olds in both adult and pediatric early phase clinical trials.  A recent study in France found that only 15% of early phase trials for cancer included teenagers between 12 and 17 years of age. The legal minimum age to participate in adult clinical trials in Europe is 18 years; the authors suggest that such “arbitrary age limits” be eliminated. (MedicalXPress)