Little is known about how trial site costs vary around the world. In this sample, most patients (60%) and sites (57%) enrolled were outside of North America. In Africa, Central Europe, Middle East, and Latin America, the cost per site was about 50% of the cost per site in North America. (PubMed)
A new study found the median cost of clinical trials in 2015 and 2016 to be $19 million, with a wide variation in costs. This study counters the assumption that elaborate and expensive clinical trials are the reason for the high costs of developing a new drug. Critics, however, argue that the study should not be misinterpreted as an estimate of drug development costs, as it has important limitations.